The seeds of Malunggay, Moringa oleifera, were extracted with distilled ethanol and concentrated under reduced pressure at 40oC. The resulting extract was partitioned between hexane, ethyl acetate, butanol and water. The solvent fractions were likewise concentrated under reduced pressure. The crude ethanol extract of dried seeds inhibited the carrageen an-induced inflammation in the hind paw of mice by 85% at a dosage of 3 mg/g body weight while the mature green seeds by 77%. The hexane fraction of the crude ethanol extract of the dried seeds also inhibited inflammation by 77% at the same dose while both butanol and water fractions inhibited inflammation by only 34%. These results indicate the strong anti-inflammatory activities of the ethanol extract and the hexane fraction. On the other hand, the ethyl acetate fraction caused a 267% increase in inflammation and exhibited toxicity. The mice died after oral administration of the fraction. The crude ethanol extract also inhibited the formation of Epstein-Barr virus-early antigen (EBV-EA) induced by 12-0-tetradecanoylphorbol-13-acetate (TPA). Aqueous extract of bark of Moringa oleifera administered orally, in previously producing stone in albino rats of Wistar strains and it was found that aqueous extract of bark of Moringa oleifera shown its antiurolithiatic activity in albino rats of Wistar strains by reducing the weight of the stone.
Moringa (Malunggay) is considered the most nutrient rich plant in the world with 46 anti oxidants, 36 anti imflamatory agents, 27% protein, more than twice the calcium content in yogurt, enzymes, vitamins and minerals in high dosages and all essential amino acids. In total more than 92 nutrients.